Bandage Contact Lenses for Corneal Abrasions

• Status: Unknown status
• Trial end date: 2019-03-01
• Target enrollment: 0
• Participant gender: All

Summary

Two percent of all patients presenting to the Emergency Departments have complaints involving the eye. Corneal abrasions are a common diagnosis with patients with eye pain and often cause significant discomfort. Current treatment includes a thorough evaluation of the eye followed by patching, empiric antibiotics, cycloplegics and oral pain medicines. This study will be a randomized controlled trial to determine the safety and efficacy of BCLs. It will involve the initial patient evaluation followed by a return visit to the Emergency Department within 36 hours for re-examination. At each visit, the patient will be assessed for the size and location of the abrasion along with their report of pain using a visual analog scale. Data will be recorded on a standard data collection sheet. Telephone contact will be made at 30 days to ensure resolution of abrasion and that no complications ensued.

• Phase: Phase 2
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Los Angeles Biomedical Research Institute; Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
• Treatments: Hydrocodone; Ophthalmic Solutions; Tetrahydrozoline

Criteria

Inclusion Criteria:

• Subjects between ages 18-65 years who present to the emergency department.

• Traumatic corneal abrasion not associated with contact lens use or communicating or adjacent wounds to the eye.

Exclusion Criteria:

• Pregnant women

• Breast-feeding women

• Corneal abrasion associated with the wearing contact lenses

• Evidence of corneal ulcer, glaucoma or other ocular pathology, monocular vision

• Wound healing deficits such as collagen vascular disease or concomitant steroid use

• Use of other ocular medications, dry eyes, blepharitis

• Systemic infections

• Known allergies to medicines used in the study