Behavioral Activation Intervention for Smoking Cessation in Smokers With Depressive Symptoms
Status:
Completed
Trial end date:
2016-05-01
Target enrollment:
Participant gender:
Summary
Depression related vulnerabilities are highly comorbid with smoking behavior and dramatically
reduce cessation rates among both community and clinical samples. Previous research has
examined the efficacy of cognitive-behavioral treatment for individuals with a history of
major depressive disorder (MDD) in standard cessation treatment. A broader health impact can
be achieved by targeting individuals with current elevated depressive symptoms to address
their association with cessation failure. Thus the objective of the present proposal is to
conduct a Stage II randomized controlled trial (RCT) comparing the behavioral activation
intervention to standard treatment among a similar community sample of 200 adult smokers with
elevated depressive symptoms. Participants will be followed over 52 weeks post-quit date and
the larger sample size will allow for more complex analysis of cessation outcomes.
Phase:
Phase 2
Details
Lead Sponsor:
University of Maryland University of Maryland, College Park
Collaborators:
National Institute on Drug Abuse (NIDA) National Institutes of Health (NIH)