Benefits of Morphine Gel for Pain Reduction in Patients With Cancer Wounds

• Status: Not yet recruiting
• Trial end date: 2024-04-01
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to compare in compare pain reduction in patients with malignant wounds using morphine gel or lidocaine gel. The main question to be answered is:

• Does morphine gel offer better pain control in malignant wounds when compared to lidocaine gel? Participants will answer a questionnaire where they report a note for pain at the site of the malignant wound and then the dressing will be performed by a nurse from the research team. The patient and the nurse do not know which product is being used. At the end of the dressing, the patient answers a new questionnaire. This process will be carried out for 3 days.

The researchers will compare the intervention group (morphine gel) and the control group (lidocaine gel) and verify if there is a difference in pain reduction between the two products.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Instituto Nacional de Cancer, Brazil
• Treatments: Lidocaine; Morphine

Criteria

Inclusion Criteria:

• Malignant neoplastic wound in breast or head and neck;

• Malignant neoplastic wound with staging >= II;

• KPS >=30%

• Having at least 3 on the numerical pain rating scale (0-10);

• Admission time equal to or greater than 48 hours.

• Make use of systemic morphine.

Exclusion Criteria:

• Wound with fistula;

• Wound with extensive coagulation necrosis (>50% of wound area;

• Exuding wound > 1 (PUSH Scale);

• Bleeding wound >1 (VIBe Scale)

• Ongoing radiotherapy on the wound.