Bepreve vs. Alrex in Subjects With Moderate to Severe Allergic Conjunctivitis
Status:
Completed
Trial end date:
2012-12-01
Target enrollment:
Participant gender:
Summary
Allergic conjunctivitis (AC) afflicts approximately 20% of the US population. Typically,
patients manifest symptoms in the spring, summer and fall, when airborne allergens are at
their peak. Patients may also be afflicted year-round, if sensitive to allergens such as dust
mites or pet dander. Signs and symptoms of allergic conjunctivitis are conjunctival
hyperemia, ocular itching, conjunctival and eyelid edema, papillary hypertrophy, tearing and
burning.
This is a randomized clinical study to evaluate the efficacy of Bepreve® (bepotastine
besilate 1.5% ophthalmic solution) compared to Alrex® (loteprednol etabonate 0.2%) in the
treatment of moderate to severe allergic conjunctivitis in patient over the age of 18 years.
The study will be a two-week study with four visits. Ocular signs (eye redness( and symptoms
(itching) will be monitored as outcome variables.
Phase:
Phase 4
Details
Lead Sponsor:
Southern California College of Optometry Southern California College of Optometry at Marshall B. Ketchum University