Beta Blocker Effects in Traumatic Brain Injury

• Status: Recruiting
• Trial end date: 2022-03-01
• Target enrollment: 0
• Participant gender: All

Summary

The study will be conducted on polytrauma patient who are admitted from emergency room or postoperative with head trauma to evaluate effects of beta blocker on patients with TBI.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Menoufia University
• Treatments: Propranolol

Criteria

Inclusion Criteria:

• GCS preoperative >10

• Abbreviated Injury Scale (AIS) >3

• Length stay in ICU >48 h

Exclusion Criteria:

• Hypersensitivity to propranolol

• Asthmatic patient

• COPD

• History of smoking

• Any cardiac problems eg: ( heart failure or HB )

• pheochromocytoma

• Pregnant patient

• Length stay <48h

• Death within 48 h of admission

• Patient who previously received any beta blocker at home.

• Symptomatic Bradycardia <60 b/m (sick sinus syndrome)

• Hemodynamic unstable patients