Overview Beta-Blocker Evaluation in Survival Trial (BEST) Status: Completed Trial end date: 1999-09-01 Target enrollment: Participant gender: Summary To determine if addition of a beta-blocker to standard therapy in Class III and Class IV heart failure patients reduced total mortality. Phase: Phase 3 Details Lead Sponsor: National Heart, Lung, and Blood Institute (NHLBI)Treatments: Adrenergic AgentsAdrenergic beta-Antagonists