Betamethasone (Betapred®) as Premedication for Reducing Postoperative Vomiting and Pain After Tonsillectomy

• Status: Recruiting
• Trial end date: 2022-06-15
• Target enrollment: 0
• Participant gender: All

Summary

Betamethasone is currently given routinely in conjunction with tonsillectomy surgery at the majority of Ear, Nose & Throat clinics in Sweden. The scientific evidence regarding the effects of betamethasone in adults is limited when it comes to postoperative nausea (PONV), pain and postoperative bleeding.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Umeå University
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate; Pharmaceutical Solutions

Criteria

Inclusion Criteria:

Signed informed consent Age over 12 years Planned for elective bilateral tonsillectomy

Exclusion Criteria:

• • Insulin dependent diabetes mellitus

• NSAID or corticosteroid intolerance

• Pregnancy

• Gastric ulcer

• Immunodeficiency

• Treatment for chronic pain

• Psychiatric disorders