Betamethasone Dosing Interval - 12 or 24 Hours?

• Status: Completed
• Trial end date: 2009-10-01
• Target enrollment: 0
• Participant gender: Female

Summary

The purpose of this study is to determine if there may be a benefit to the newborn if betamethasone is given 12 hours apart instead of 24 hours apart.

• Phase: N/A
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: The Cooper Health System
• Treatments: Betamethasone; Betamethasone benzoate; Betamethasone sodium phosphate; Betamethasone Valerate; Betamethasone-17,21-dipropionate

Criteria

Inclusion Criteria:

• Pregnant women expected to deliver preterm (either induced or spontaneously) for any obstetrical or medical indication.

• Gestational age between 23 and 34 weeks gestational age.

• Dating must either be by LMP which is consistent with ultrasound performed at any gestational age, or calculated by a sonogram less than or equal to 23 weeks.

Exclusion Criteria:

• Patients at <23 or >34 weeks gestational age.

• Known drug allergy to betamethasone.

• Given steroid other than betamethasone for lung maturation.

• Any contraindication to steroid therapy.