Overview

Bevacizumab and ICIs + hSRT in Symptomatic Melanoma Brain Metastases

Status:
Not yet recruiting
Trial end date:
2026-01-30
Target enrollment:
Participant gender:
Summary
Single arm phase I/II trial to evaluate the safety and efficacy of the combination of bevacizumab, with ipilimumab plus nivolumab, and hypofractionated stereotactic radiotherapy (hSRT) in patients with symptomatic melanoma brain metastases (MBM).
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Melanoma and Skin Cancer Trials Limited
Treatments:
Bevacizumab
Ipilimumab
Nivolumab