Bilastine Updosing in Chronic Spontaneous Urticaria
Status:
Completed
Trial end date:
2016-03-01
Target enrollment:
Participant gender:
Summary
Chronic spontaneous urticaria (CSU), formerly also known as chronic idiopathic urticaria and
chronic urticaria (CU), is one of the most frequent skin diseases. At any time, 0.5-1% of the
population suffers from the disease. Although all age groups can be affected, the peak
incidence is seen between 20 and 40 years of age. The duration of the disease is generally
several years but is likely to be longer in more severe cases, cases with concurrent
angioedema, in combination with physical urticaria or with a positive autologous serum skin
test (autoreactivity). CSU has major detrimental effects on quality of life, with sleep
deprivation and psychiatric comorbidity being frequent. It also has a large impact on society
in terms of direct and indirect health care costs as well as reduced performance at work and
in private life.