Biliary Excretion of Conjugated Bile Acids in Humans Measured by 11C-cholylsarcosine PET/CT

• Status: Completed
• Trial end date: 2014-09-01
• Target enrollment: 0
• Participant gender: All

Summary

We wish to develop a protocol for PET/CT examination of humans using the bile acid tracer 11C-cholylsarcosine. This is done by a series of PET/CT examinations of healthy humans and patients with cholestatic disorders.

• Phase: Phase 1
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Aarhus
• Treatments: Bile Acids and Salts; Cholylsarcosine

Criteria

Inclusion Criteria:

• Patients with cholestatic disorders and healthy subjects

Exclusion Criteria:

• Body weight above 110 kg (catheterization problematic).

• Diabetes

• Pregnant or breast feeding women.