Bioavailability of Vagantin® Coated Tablets Relative to an Oral Methantheline Bromide Solution
Status:
Completed
Trial end date:
2000-01-01
Target enrollment:
Participant gender:
Summary
The primary objective of the study is:
•To describe extent and rate of absorption of methantheline after single oral dose
administration of Vagantin® coated tablets (Test) in comparison to a methantheline bromide
solution (Reference)
The secondary objectives of the study are:
- To determine elimination the half-life of methantheline bromide
- To describe the effects of Test and Reference on salivation, accommodation, pupil
response, blood pressure and heart rate
- to assess frequency and intensity of adverse drug reactions