Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease

• Status: Completed
• Trial end date: 2014-11-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if high doses of vitamin D3 administered orally as adjunct therapy to children with Crohn's disease could improve the outcome of the disease.

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: St. Justine's Hospital
• Treatments: Cholecalciferol; Ergocalciferols; Vitamin D; Vitamins

Criteria

Inclusion Criteria:

• Age between 10 and 18 years

• Crohn's disease diagnosed by usual clinical and endoscopic criteria

• Recent (less than one week) blood test with results of : Albumin, sedimentation rate, hematocrit

Exclusion Criteria:

• Known renal or cardiac malformation

• Disorders of phospho-calcic metabolism and vitamin D

• Intake of vitamin D supplementation in the last three months prior to enrollment

• Current intake of medications known to interfere with the metabolism of calcium, phosphate and vitamin D *