Biomarker-Guided Fluorouracil in Treating Patients With Colorectal Cancer Receiving Combination Chemotherapy
Status:
Completed
Trial end date:
2013-09-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Drugs used in chemotherapy, such as fluorouracil, oxaliplatin, and leucovorin
calcium, work in different ways to stop the growth of tumor cells, either by killing the
cells or by stopping them from dividing. Giving more than one drug, combination chemotherapy,
may kill more tumor cells. Studying samples of blood in the laboratory from patients with
cancer receiving fluorouracil in combination with oxaliplatin and leucovorin calcium may help
doctors learn how fluorouracil works in the body and how patients will respond to treatment.
PURPOSE: This phase I trial is studying biomarker-guided fluorouracil in treating patients
with colorectal cancer receiving combination chemotherapy.