Biomarker Strategies for Medication-Enhanced Cognitive Training in Schizophrenia
Status:
Completed
Trial end date:
2019-06-01
Target enrollment:
Participant gender:
Summary
Cognitive training is moderately effective at reducing symptoms and improving life function
in schizophrenia patients. The present application develops a strategy for increasing the
effectiveness of cognitive training through the use of pro-cognitive medications. Specific
biomarkers will be studied that identify patients most sensitive to these pro-cognitive
medications, to test the feasibility of using these biomarkers in a large clinical trial of
medication-enhanced cognitive training in schizophrenia.