Bipolar Disorder in Late Life

• Status: Completed
• Trial end date: 2011-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to look at certain structural changes in the brain in people with bipolar disorder or those with a history of Bipolar disorder.

• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Duke University
• Treatments: Valproic Acid

Criteria

Inclusion Criteria:

1. DSM-IV diagnosis of bipolar Disorder, Manic and mixed episodes.

2. 18 years of age and older, male or female, any race.

3. Capacity to give informed consent and follow study procedures.

Exclusion Criteria:

1. History of alcohol/drug dependence

2. Any metal or pacemaker in the body which precludes MRI

3. Pregnancy

4. Dementia or other primary psychiatric disorders including substance abuse/dependence, anxiety disorders, schizophrenia

5. For controls, numbers one through four above as well as any history of depression or the use of antidepressants