Bispectral Index Guiding Etomidate Used in Children Aged 3 to 10 for Clinical Anesthesia Induction

• Status: Unknown status
• Trial end date: 1969-12-31
• Target enrollment: 0
• Participant gender: All

Summary

This research through using bispectral index to guide the induced dose and speed of etomidate lipid emulsion for pediatric total venous anesthesia,and to provide a reference for clinical anesthesia physician.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Henan Provincial Hospital; Henan Provincial People's Hospital
• Treatments: Anesthetics; Etomidate; Propofol; Sevoflurane

Criteria

Inclusion Criteria:

1. obtain informed consent;

2. undergoing elective hypospadias repair surgery under general anesthesia;

3. American society of anesthesiologists (ASA) class I-II;

4. aged between 3-10 years old;

5. BMI is 18.5-30 kg/m2;

Exclusion Criteria:

1. systolic blood pressure≥180 mmHg or<90 mmHg, diastolic blood pressure≥110 mmHg or<60 mmHg;

2. serious heart, brain, liver, kidney, lung, endocrine diseases or serious infections;

3. long-term use of hormone or a history of adrenal cortex inhibition;

4. suspected or confirmed difficult airway;

5. suspected or confirmed abuse of narcotic analgesic drugs, psychotropic drugs;

6. neuromuscular disease;

7. mental instability, or have a mental illness;

8. allergic to investigational products or with other contraindication

9. participated in other study within 30 days