Blood Flow and Vascular Function in Cystic Fibrosis
Status:
Completed
Trial end date:
2018-07-01
Target enrollment:
Participant gender:
Summary
Cystic fibrosis (CF) has many health consequences. A reduction in the ability to perform
exercise in patients with CF is related to greater death rates, steeper decline in lung
function, and more frequent lung infections. However, the physiological mechanisms for this
reduced exercise capacity are unknown. The investigators laboratory recently published the
first evidence of systemic vascular dysfunction in patients with CF. Therefore, it is
reasonable to suspect that the blood vessels are involved with exercise intolerance in CF.
This study will look at how 1) blood flow and 2) artery function contribute to exercise
capacity in CF.
Phase:
Phase 2
Details
Lead Sponsor:
Augusta University National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborator:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)