Blood Levels of Abacavir After One Dose in HIV-Infected Children and Adolescents
Status:
Completed
Trial end date:
2002-08-01
Target enrollment:
Participant gender:
Summary
The purpose of this study is to measure blood levels of abacavir in children and adolescents
over a period of time following a single dose so that a dosage for adolescents can be
determined.
Little is known about how abacavir is cleared by the body in adolescents. It has been shown
that young children require a higher abacavir dose based on weight than adults. Older
children, or adolescents, may not require as high a dose. This study may provide information
as to whether the children's dose or the adult dose is better for HIV-infected adolescents.
Phase:
Phase 1
Details
Lead Sponsor:
National Institute of Allergy and Infectious Diseases (NIAID)
Collaborator:
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)