Blood Loss Reduction After Total Knee Arthroplasty. Comparison Topical Tranexamic Acid vs Platelet Rich Plasma

• Status: Completed
• Trial end date: 2017-03-09
• Target enrollment: 0
• Participant gender: All

Summary

The investigators will include patients who will be schedule for total knee arthroplasty with a diagnosis of osteoarthritis. The patients will be divided in two groups. In both groups a verbal and clear detailed information will be given on the intraoperative approach. The first group will receive topical tranexamic acid and the second group topical platelet rich plasma; both in the surgical site. Both groups will be assessed before and after the intervention with laboratory results (hemoglobin, hematocrit levels) and drainage drain.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Universidad Autonoma de Nuevo Leon
• Treatments: Tranexamic Acid

Criteria

Inclusion Criteria:

1. Age >18 years

2. Patient candidates for primary total knee replacement

3. Patients willing to participate in the study and sign de inform consent

Exclusion Criteria:

1. Patients with previous history of thromboembolic event in the last 6 months

2. Patients candidates for revision total knee replacement

3. Patients candidates for tumoral total knee replacement

4. Patients candidates for bilateral total knee replacement

5. Patient with cognitive deficit

6. Previous history of coagulopathy