Overview

Body Composition in Infants With Klinefelter Syndrome and Effects of Testosterone Treatment

Status:
Completed
Trial end date:
2020-01-01
Target enrollment:
Participant gender:
Summary
This research study in infant males with Klinefelter syndrome (47,XXY) will learn more about body composition (muscle and fat) and male hormones and look at the effect of testosterone shots on body composition. The Investigators know that older boys and men with Klinefelter syndrome often have more fat compared to muscle than adults without Klinefelter syndrome, but we do not know if this difference is present at birth or develops over time. The Investigators will learn if body composition and motor skills are improved with testosterone treatment in infants with Klinefelter syndrome.
Phase:
Phase 4
Details
Lead Sponsor:
University of Colorado, Denver
Treatments:
Methyltestosterone
Testosterone
Testosterone 17 beta-cypionate
Testosterone enanthate
Testosterone undecanoate