Boric Acid in Degree 2 Furcation Defect

• Status: Completed
• Trial end date: 2016-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this double-masked, randomized, controlled clinical trial was to evaluate the effects of subgingival delivery of boric acid gel as an adjunct to scaling and root planing (SRP) on clinical and radiographic parameters and compare this method with SRP plus placebo gel alone in patients with chronic periodontitis (CP).

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Government Dental College and Research Institute, Bangalore
• Treatments: Tetrahydrozoline

Criteria

Inclusion Criteria:

• Presence of buccal Class II furcation defects in endodontically vital, asymptomatic mandibular first and second molars with a radiolucency in the furcation area on an intraoral periapical radiograph with probing depth (PD) ≥ 5mm and horizontal ≥ PD 3mm after phase I therapy i.e, scaling and root planing (SRP)

• No history of antibiotic or periodontal therapy in the preceding 6 months

Exclusion Criteria:

• Systemic conditions known to affect the periodontal status

• Medications known to affect the outcomes of periodontal therapy

• Hematological disorders and insufficient platelet count (<200,000/mm3)

• Pregnancy/lactation

• Smoking and tobacco use in any form

• Immunocompromised individuals

• Those having unacceptable oral hygiene (plaque index [PI] >1.5)

• Teeth with furcation involvement, non-vital teeth, and carious teeth indicated for restorations and mobility of at least grade II

• Aggressive periodontitis