Bortezomib, Paclitaxel, and Carboplatin in Treating Patients With Metastatic Melanoma
Status:
Completed
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
This phase II trial is studying how well giving bortezomib together with paclitaxel and
carboplatin works in treating patients with metastatic melanoma. Bortezomib may stop the
growth of tumor cells by blocking some of the enzymes needed for cell growth. Drugs used in
chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth
of tumor cells, either by killing the cells or by stopping them from dividing. Bortezomib may
help paclitaxel and carboplatin kill more tumor cells by making tumor cells more sensitive to
these drugs