Bortezomib and Topotecan in Treating Patients With Advanced Solid Tumors
Status:
Completed
Trial end date:
2008-06-01
Target enrollment:
Participant gender:
Summary
RATIONALE: Bortezomib may stop the growth of tumor cells by blocking some of the enzymes
needed for cell growth. Drugs used in chemotherapy, such as topotecan, work in different ways
to stop the growth of tumor cells, either by killing the cells or by stopping them from
dividing. Giving bortezomib together with topotecan may kill more tumor cells.
PURPOSE: This phase I trial is studying the side effects and best dose of bortezomib and
topotecan in treating patients with advanced solid tumors.