Botox as a Treatment for Interstitial Cystitis in Women
Status:
Completed
Trial end date:
2010-09-01
Target enrollment:
Participant gender:
Summary
Patients with interstitial cystitis have been well documented to have pelvic floor muscle
tenderness as well as pain on bladder distension. Some investigators have even suggested that
pelvic floor muscle pain is primarily the cause of bladder problems.
Botulinum toxin A causes muscle relaxation by inhibiting the acetylcholine release at the
neuromuscular junction. It has been shown that this mechanism relieves pain in a number of
muscle spasm-related syndromes.
Because, at present, there is little effective therapy available for patients with
interstitial cystitis, the researchers want to determine if botulinum toxin A will relieve
bladder and pelvic pain in these patients.
Phase:
Phase 4
Details
Lead Sponsor:
University of Washington
Collaborator:
Paul G. Allen Family Foundation
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA