Botox for the Treatment of Chronic Exertional Compartment Syndrome
Status:
Recruiting
Trial end date:
2022-03-01
Target enrollment:
Participant gender:
Summary
After diagnosis of Chronic Exertional Compartment Syndrome (CECS), the participants will be
referred to both physical therapy and Botox injection. In physical therapy, the therapist
will perform strength measurements of the lower leg (ankle plantarflexion and dorsiflexion)
which will be repeated 2 months following the injection. An ultrasound-guided injection of 50
units of Botox will be administered into the tibialis anterior. 25 units will be injected
into two different spots in the muscle one being more proximal and the other distal. This
will be a one-time injection and will be observed as to how it effects participant symptoms
over the next 6 months at either a clinic visit (at 2 months) or telephone call (at 4 and 6
months after injection) via the University of Wisconsin Running Index. Two months following
the injection, the participant will undergo repeat measurements of strength using the Kiio
Force Sensor.
Should potential participants of childbearing potential wish to enroll in the study, a urine
pregnancy test will be performed prior to enrollment; participants will not be enrolled if
test is positive.