Botulinim Toxin Type A Injections by Different Guidance in Stroke Patients With Spasticity on Upper Extremities

• Status: Unknown status
• Trial end date: 2016-07-01
• Target enrollment: 0
• Participant gender: All

Summary

The aims of this study were to compare the injection locations of key spastic muscles on upper extremity by three different guidance localization methods ( surface anatomy landmark, ultrasonography, electric stimulation) and the effectiveness.

• Phase: Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Chang Gung Memorial Hospital
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• first onset.

• at least onset before 6 months.

• elbow, wrist and fingers are above Modified Ashworth Scale(MAS) 1+.

• Mini-Mental State Exam above 24.

• can follow all of the follow up and instruction.

• patients never accept botox, phenol and alcohol injections before.

Exclusion Criteria:

• contracture deformity on upper extremity.

• patients had accepted botox before or had have phenol, alcohol injections and operation 6 months ago.

• allergy to botox.

• have neither infection nor skin disorder on inject site.

• now accept aminoglycoside or other medicine treatment which may affect neuromuscular transition.

• combine other systemic disease of neurological or skelectomuscular system

• cognition disorder or aphasia after stroke.