Botulinum-A Toxin Injection for Detrusor Hyperreflexia in Spinal Cord Injury: A Non-Surgical Approach.
Status:
Withdrawn
Trial end date:
1969-12-31
Target enrollment:
Participant gender:
Summary
The purpose of the study is to determine whether Botulinum-A toxin injected in the bladder
muscle will help prevent the frequency and degree of urinary incontinence in Spinal Cord
Injured and Multiple Sclerosis patients. The proposed mechanism would be that the Toxin would
allow the bladder to hold more urine at a lower pressure as determined by Urodynamics. The
research will answer the question whether the dosages 300 units vs 400 units are either
equally vs not equally effective in helping urinary incontinece and bladder storage.
Phase:
Phase 2
Details
Lead Sponsor:
US Department of Veterans Affairs VA Office of Research and Development
Treatments:
abobotulinumtoxinA Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA