Botulinum Toxin A for Treatment of Catocholamine Induced Finger Necrosis
Status:
Unknown status
Trial end date:
2013-12-01
Target enrollment:
Participant gender:
Summary
Patients in the intensive care unit (ICU) often require blood pressure support of vasoactive
drugs such as amines. Finger necrosis (so called "blue toe syndrome") is a well documented
phenomena with incidence reaching as high as 60% in patients receiving vasopressin. Botulinum
toxin is a known muscle relaxant used for a variety of medical application. Recently, several
reports have demonstrated its effect in vasospastic disorders. It has also been in mice that
when administered locally it has a local vasodilatory effect. The goal of this experiment is
to compare the effect of Botulinum Toxin administered locally on amine induced finger
necrosis.
Phase:
Phase 4
Details
Lead Sponsor:
Sheba Medical Center
Treatments:
abobotulinumtoxinA Botulinum Toxins Botulinum Toxins, Type A incobotulinumtoxinA onabotulinumtoxinA