Botulinum Toxin A for the Treatment of Keratoconus

• Status: Completed
• Trial end date: 2014-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to associate the use of botulinum toxin type A for patients with keratoconus to demonstrate that tension eyelid has an important role in disease progression.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Federal University of São Paulo
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• patients with documented keratoconus

• best-corrected visual acuity measurable at refraction test

• age between 10-40 years

• good health

• understand the procedure and its limitations

Exclusion Criteria:

• only one functional eye

• previous ocular surgery

• concurrent corneal infection and other ocular diseases that modified the visual acuity

• known allergy to botulinum toxin

• pregnancy

• poor collaboration for performing the examinations and the procedure