Botulinum Toxin Injection for Preventing Secondary Atrial Fibrillation in Patient With Supra-ventricular Tachyarrythmias

• Status: Unknown status
• Trial end date: 2016-02-01
• Target enrollment: 0
• Participant gender: All

Summary

The investigators have conducted a prospective, double-blind, randomized study to assess the comparative safety and efficacy of two different ablation strategies, RFA versus RFA plus botulinum toxin injection, in patients with supra-ventricular tachyarrhythmias. Results were assessed with the use of an implanted monitoring device (IMD).

• Phase: Phase 2
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Meshalkin Research Institute of Pathology of Circulation
• Treatments: Botulinum Toxins

Criteria

Inclusion Criteria:

• atrial flutter, AV nodal re-entry tachycardia, focal atrial tachycardia, WPW syndrome

• secondary atrial fibrillation

Exclusion Criteria:

• congestive heart failure

• LV ejection fraction < 35%

• left atrial diameter > 60 mm