Botulinum Toxin Injection for Treatment of Vaginismus

• Status: Unknown status
• Trial end date: 2008-04-01
• Target enrollment: 0
• Participant gender: Female

Summary

According to high rate of vaginismus (about 10 percent) which leads to unconsummated marriage (about 1 percent) and low efficacy for conventional treatments such as biofeedback therapy, analgesic drugs and pain killers and surgical treatment, there's necessity to find more effective method.

In our previous study, injecting botulinum toxin in 23 patients cured 75% of them.Now we are to make comparison between different doses of toxin injection and record the patient sexual satisfaction.

• Phase: Phase 3
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: Tehran University of Medical Sciences
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• Unconsummated marriage

• Difficult mating

• No response to biofeedback

Exclusion Criteria:

• Patient unlikely to have toxin injection

• Not having mutual life with partner

• Non treated pelvic and vaginal infection