Botulinum Toxin Versus Active Strength Training in the Treatment of Lateral Epicondylitis

• Status: Completed
• Trial end date: 2014-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to compare efficacy, feasibility and cost effectiveness of botulinum toxin type A injections to active nine weeks strength training and stretching program in the treatment of the chronic lateral epicondylitis.

The main hypothesis is that the botulinum toxin type A injections may enable more rapid pain relief while strength training may provide better functional results and less relapses during the follow-up.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Seinajoki Central Hospital
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A; incobotulinumtoxinA; onabotulinumtoxinA

Criteria

Inclusion Criteria:

• pain at the lateral side of the elbow over 3 months

• local tenderness on palpation over the lateral epicondyle

• positive Mill's sign

• lateral elbow pain progression on resisted wrist and/or middle finger extension

• involved in working life

Exclusion Criteria:

• bilateral symptoms or simultaneous medial epicondylitis

• verified or suspected cervical radiculopathy or affected limb neuropathy

• congenital or acquired deformities of the elbow

• previous surgery of the elbow

• infection, dislocation, tendon ruptures, or fractures in the area

• systemic musculoskeletal or neurological disorders, incl. rheumatic diseases and fibromyalgia

• allergy, antibodies or other contraindications for botulinum toxin

• severe depression, chronic pain syndrome or somatisation disorder

• ongoing retirement process

• pregnancy or breastfeeding

• current participation in other clinical trials