Botulinum Toxin for Erectile Dysfunction

• Status: Completed
• Trial end date: 2019-01-10
• Target enrollment: 0
• Participant gender: Male

Summary

To evaluate the safety and efficacy of intra-cavernosal Botulinum toxin injection as an alternative line of treatment in patients with erectile dysfunction - not responding to oral PDE5i - through cavernosal smooth muscle relaxation.

• Phase: Phase 2/Phase 3
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Cairo University
• Treatments: abobotulinumtoxinA; Botulinum Toxins; Botulinum Toxins, Type A

Criteria

Inclusion Criteria:

• 70 males will be included in the study recruited from Andrology, Sexology & STD's outpatient clinic, Kasr El Aini Hospitals, Cairo University, complaining of ED.

• Unable to develop erections sufficient for intercourse.

• Failing to respond to first line and second line treatments for Erectile Dysfunction with surgery as the only remaining treatment option.

• Age between 18 to 80 years.

Exclusion Criteria:

• Significant cardiovascular disease interfering with sexual activity