Overview

BrEPEM-LH-22017 for Older Patients With Untreated Hodgkin Lymphoma (HL)

Status:
Active, not recruiting
Trial end date:
2023-10-30
Target enrollment:
Participant gender:
Summary
The purpose of the phase Ib of the study is to identify the maximum tolerated dose (MTD) of Brentuximab Vedotin (BV) in combination with EPEM and to assess the toxicity of the combination of BV with EPEM. In the phase II efficacy will be evaluated.Besides, progression-free survival (PFS), event-free survival (EFS), overall survival (OS), the duration of response, the overall response rate (ORR) based on best response will be evaluated
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Grupo Español de Linfomas y Transplante Autólogo de Médula Ósea
Collaborator:
Takeda
Treatments:
Cyclophosphamide
Etoposide
Etoposide phosphate
Mitoxantrone
Prednisone
Procarbazine