Brachial Plexus Blockade Two Days Before Surgery Can Improve Postoperative Analgesia

• Status: Suspended
• Trial end date: 2025-12-30
• Target enrollment: 0
• Participant gender: All

Summary

Intense e recurrent nociceptive stimulation, which occurs in the postoperatively, can trigger sensitization of the peripheral and central nociceptive pathway, leading to chronic pain. Patients with rotator cuff injury often present to surgery due to referred moderate to intense long-term pain. During the immediate postoperative period, pain is rare due to the routine administration of a brachial plexus blockade as an adjuvant to improve the quality of postoperative analgesia. However, after the second postoperative day, the effect of the blockade ceases, and the pain becomes high and hard to treat, leading the patient to request administration of more frequent and more potent analgesics. The aim of this project is to assess the postoperative analgesic benefits of a brachial plexus blockcade 2 days before arthroscopic surgical correction of rotator cuff injury by reducing the sensitization of the nociceptive pathway.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: University of Sao Paulo General Hospital

Criteria

Inclusion Criteria:

• Body mass index < 35 kg/m²

• shoulder pain lasting > 3 months

• pain score > 3 (visual analog scale and verbal response 0 to 10) on the day of pre anesthetic evaluation

• American Society of Anesthesiologists score I or II

• mentally and legally capable to understand and consent to study participation.

Exclusion Criteria:

• Allergy to any medication of the trial

• refusal to participate, contraindication to any medication or technique described in the protocol of the trial

• complications from, or failure of brachial plexus blockade.