Overview

Breast Capsular Contracture Following Post-Mastectomy Reconstruction in Women Treated With the Leukotriene Inhibitor Zafirlukast: A Phase II Trial

Status:
Terminated

Trial end date:
2018-12-20

Target enrollment:

Participant gender:

Summary

A 2 arm, 90 patient (45 per cohort) trial in patients with breast cancer who will be undergoing mastectomy with immediate tissue-expander reconstruction to determine whether treatment with zafirlukast (20mg PO BID) can reduce or prevent the development of capsular contracture.

Phase:

Phase 2

Details

Lead Sponsor:

University of California, San Francisco

Treatments:

Leukotriene Antagonists
Zafirlukast