Overview

Brigatinib in Pediatric and Young Adult Patients With ALK+ ALCL, IMT or Other Solid Tumors

Status:
Not yet recruiting
Trial end date:
2030-12-01
Target enrollment:
Participant gender:
Summary
This is an open-label, phase I-II dose-escalation and expansion study designed to define the recommended dose of brigatinib as monotherapy in pediatric and young adult patients with ALK+ ALCL, IMT or other solid tumors and to evaluate the pharmacokinetics (PK), (long-term) safety, and efficacy of brigatinib in these children.
Phase:
Phase 1/Phase 2
Details
Lead Sponsor:
Princess Maxima Center for Pediatric Oncology
Collaborator:
Takeda