In this study the investigators will examine the effect of dopamine (bromocriptine) on
insulin sensitivity in lean and obese subjects. Furthermore, the investigators will examine
whether the timing of bromocriptine administration has influence on insulin sensitivity.
To do so, the investigators will include lean and obese subjects who will use 2 times 2 weeks
bromocriptine. In randomized order, they will use it in the morning or in the evening.
The investigators will examine insulin sensitivity by performing a 7-point oral glucose
tolerance test.
Furthermore, the investigators will examine energy expenditure and subjects will keep track
of their eating behaviour in the 3 days before each study visit.
Phase:
N/A
Details
Lead Sponsor:
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)