Bryophyllum Pinnatum Versus Solifenacin Versus Placebo for Overactive Bladder
Status:
Terminated
Trial end date:
2017-07-09
Target enrollment:
Participant gender:
Summary
Overactive bladder (OAB) is an enigmatic condition that is treated symptomatically with
anticholinergic drugs (gold standard 2013). In a clinical pilot study was found to be a trend
for a higher reduction of the micturition frequency in the Bryophyllum pinnatum group -
treated with chewing tablets containing 50% of dried BP leaf press juice - than in the
placebo group (n=20, p=0.064) Hypothesis: To test the superior effectivity of Bryophyllum
versus Placebo in the treatment of OAB with the needed number (Purpose 1) and to assess in an
experimental arm the side effects of BP in comparison to the standard drug (Vesicare) in a
clincial trial (Purpose 2).
Phase:
Phase 2/Phase 3
Details
Lead Sponsor:
University of Zurich
Collaborators:
Dr. med. David Scheiner Dr. med. Matthias Werner PD Dr. med. Verena Geissbühler Prof. pharm. Ursula von Mandach