Budesonide for Emergency Treatment of Acute Wheezing in Children

• Status: Completed
• Trial end date: 2009-12-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to determine if adding nebulized budesonide to the systemic steroid for treatment of acute wheezing has any additive benefit in the emergency room.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Kecioren Education and Training Hospital
• Treatments: Budesonide

Criteria

Inclusion Criteria:

• Children who have recurrent wheezing attacks and admitted to the emergency room for acute wheezing

• Pulmonary index score of 7-13

• Parental/guardian permission (informed consent) and if appropriate, child assent

Exclusion Criteria:

• Systemic corticosteroid use in the last 30 days

• Chronic lung diseases including cystic fibrosis

• Immunodeficiency

• Cardiac disease requiring surgery or medications

• Adverse drug reaction or allergy to budesonide, albuterol, ipratropium bromide, prednisone, prednisolone, or methylprednisolone

• Known renal or hepatic dysfunction

• Impending respiratory failure requiring positive pressure ventilation

• Immune deficiency

• Gastroesophageal reflux disease

• Suspected foreign body aspiration or croup

• Anatomic abnormalities of the respiratory tract