Bupivacaine/Epinephrine +Dexamethasone vs. Liposomal Bupivacaine

• Status: Unknown status
• Trial end date: 2020-06-10
• Target enrollment: 0
• Participant gender: All

Summary

This study will assess analgesia after robotic lung surgery. Subjects will be randomized to receive wound infiltration and intercostal nerve block with either liposomal bupivacaine or bupivacaine/epinephrine + dexamethasone. Liposomal bupivacaine is a newer local anesthetic product and has not been compared to a combination of bupivacaine/epinephrine + dexamethasone in the context of pain control after robotic lung surgery.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Cooper Health System
• Treatments: BB 1101; Bupivacaine; Dexamethasone; Dexamethasone acetate; Epinephrine; Epinephryl borate; Racepinephrine

Criteria

Inclusion Criteria:

• undergoing robotic wedge resection or lobectomy for lung mass(es)

Exclusion Criteria:

• emergency case

• history of opiate abuse

• chronic pain syndrome

• intravenous drug use

• chronic use of oral steroids

• pregnancy

• imprisonment

• body weight lower than 70 kg

• liver failure

• uninsured patients

• non-verbal patients or patients who are unable to rate their pain on a visual analogue pain scale

• history of allergic reaction to any of the drugs used in the study: bupivacaine, liposomal bupivacaine, dexamethasone