Buprenorphine, Clonidine, and Dexamethasone on Duration of Brachial Plexus Blocks for Upper Extremity Surgery

• Status: Recruiting
• Trial end date: 2025-06-30
• Target enrollment: 0
• Participant gender: All

Summary

The goal of this clinical trial is to learn if there is a difference in morphine requirements in patients after upper extremity surgeries including shoulder arthroscopy. The main question it aims to answer is whether there is a difference between Interscalene brachial plexus blocks with the addition of buprenorphine, dexamethasone, and clonidine and the same block without the adjuvant.

• Phase: Phase 4
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Loyola University
• Treatments: BB 1101; Buprenorphine; Clonidine; Dexamethasone; Dexamethasone acetate

Criteria

Inclusion Criteria:

• Patients ≥ 18 years old

• Patients undergoing shoulder arthroscopy

• Patients willing to participate and sign informed consent

Exclusion Criteria:

• Severe COPD/other contraindication to general anesthesia

• Patient with a weight of less than 60 kg

• Dementia, not alert or oriented to person, place, or time

• Chronic pain patient with daily opioid use at home.

• Patient with allergy to local anesthetics

• Patient refusal

• Total shoulder arthroplasty

• Concomitant pain in different area from operative site.

• Pregnancy

• Patient with active infection on the injection sites for the blocks

• Patients unable or willing to understand or comply with the study protocol