Buprenorphine Treatment: A Safe Alternative for Opioid Dependent Pain Patients

• Status: Terminated
• Trial end date: 2013-08-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study is to examine whether buprenorphine can be at least as effective as other opioid medications in relieving chronic pain in patients who suffer from dependence on their opioid medications, while patients simultaneously experience progressive decline of pain along with absence of opioid withdrawal symptoms and improved quality of life.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: Maimonides Medical Center
• Treatments: Analgesics, Opioid; Buprenorphine; Buprenorphine, Naloxone Drug Combination; Naloxone

Criteria

Inclusion Criteria:

• Meets DSM criteria for opioid dependence (or opioid use disorder when DSM 5 is in use)

• Has received opioid therapy for at least 90 days

• Has opioid dependence as assessed by a Maimonides psychiatrist

Exclusion Criteria:

• Scheduled for major surgery during study duration

• Predicted life expectancy < 1 year

• Plan to cease habitation in greater New York area within 6 months

• Risks for buprenorphine outweigh potential benefit, as determined by the PI

• Lacks sufficient fluency in English to understand the study protocol, answer survey questions or give informed consent

• Pregnant women