Bupropion SR Plus Counseling for Smoking Cessation

• Status: Completed
• Trial end date: 2003-10-01
• Target enrollment: 0
• Participant gender: All

Summary

The purpose of this study was to determine if bupropion plus counseling was more effective than bupropion alone or counseling alone in helping smokers quit smoking.

• Phase: Phase 4
• Accepts Healthy Volunteers?: Accepts Healthy Volunteers

Details

• Lead Sponsor: University of Wisconsin, Madison
• Collaborators: National Cancer Institute (NCI); National Institute on Drug Abuse (NIDA)
• Treatments: Bupropion

Criteria

Inclusion Criteria:

• Smoke 10 or more cigarettes per day

• Expired carbon monoxide (CO) level greater than 9 parts per million (ppm)

• Motivated to quit smoking (score of 3 on 4-point self-report scale)

• Willing to fulfill study requirements

Exclusion Criteria:

• Carbon monoxide breath test score below 9 ppm

• Serious psychopathology (bipolar disorder, psychosis)

• Center for Epidemiologic Studies Depression Scale CES-D)score over 16

• Contraindications for use of bupropion

• History of seizure disorder

• History of eating disorder

• Current heavy drinking

• Risk of pregnancy

• Current breastfeeding