Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits
Status:
Recruiting
Trial end date:
2022-05-01
Target enrollment:
Participant gender:
Summary
This study is designed to determine whether bupropion (vs escitalopram) increases functional
connectivity (FC) within reward-related neurocircuits and decreases motivational deficits in
depressed patients with increased inflammation and anhedonia. Participants will be randomized
to take bupropion extended release (XL) or escitalopram for 8 weeks.