Bupropion and Cigarette-Related Cues in Smokers

• Status: Completed
• Trial end date: 2005-12-31
• Target enrollment: 0
• Participant gender: All

Summary

Randomized, double-blind, before-after controlled trial to assess changes in regional brain activation in response to cigarette-related cues from before to after treatment with bupropion (vs placebo).

• Phase: Phase 1

Details

• Lead Sponsor: University of California, Los Angeles
• Treatments: Bupropion

Criteria

Inclusion Criteria:

• Treatment-seeking cigarette smoker

• Meet DSM-IV criteria for nicotine dependence

• Negative result on urine test for drug use during screening

Exclusion Criteria:

• History of any Axis I psychiatric diagnosis other than nicotine dependence

• Medical conditions that might affect brain function

• Current use of medications that could alter brain function

• Pregnancy

• Current illicit drug use other than occasional use of marijuana