Buspirone for Functional Dysphagia

• Status: Completed
• Trial end date: 2017-04-12
• Target enrollment: 0
• Participant gender: All

Summary

This study evaluates the utility of buspirone in patients who have a diagnosis of functional dysphagia. All participants will be randomized to receive either a placebo pill or buspirone. Subsequently, we will evaluate whether their swallowing is improved. Participants who were randomized to receive placebo will then receive buspirone and those who were receiving buspirone will receive placebo. We will again evaluate whether their swallowing improved.

• Phase: N/A
• Accepts Healthy Volunteers?: No

Details

• Lead Sponsor: The Cleveland Clinic
• Treatments: Buspirone

Criteria

Inclusion Criteria:

• Diagnosis of IEM per Chicago Classification, v3.0 criteria - as noted above

• Esophagogastroduodenoscopy (EGD) negative for mechanical obstruction

• Esophageal biopsies negative for eosinophilic esophagitis

Exclusion Criteria:

• Pregnant women

• Prisoners

• Currently on other serotonin modulating medications