Busulfan, Fludarabine, Clofarabine With Allogeneic Stem Cell Transplantation for Acute Myeloid Leukemia
Status:
Completed
Trial end date:
2013-03-01
Target enrollment:
Participant gender:
Summary
The goal of this clinical research study is to find the best dose of clofarabine and
fludarabine that can be given with busulfan followed by an allogeneic blood stem cell
transplant. Researchers will study whether this combination can help to control the disease,
and look at the safety of this combination. Researchers also want to find out if combining
busulfan with clofarabine alone or combining busulfan with both fludarabine and clofarabine
will improve the treatment, compared with the previous standard method using busulfan and
fludarabine alone.