CACAF2 Study: Catheter Ablation for Cure of Atrial Fibrillation
Status:
Terminated
Trial end date:
2009-05-01
Target enrollment:
Participant gender:
Summary
The objective of this prospective multicenter randomized study is to establish the
effectiveness of treatment of persistent atrial fibrillation by encircling the pulmonary
veins with radiofrequency (RF) ablation and creating additional lines of block with the aid
of the NAVISTAR® THERMOCOOL® catheter in conjunction with the CARTO™ EP Navigation System.
Effectiveness will be determined by comparing the chronic success of ablation therapy versus
antiarrhythmic drug therapy, defined as the absence of persistent tachyarrhythmias during the
first 24 months after a run-in phase of 2 months.